When planning for a trip and starting that initial hotel search, I highly recommend going to Tablet Hotels. The website is clean and easy to navigate and also showcases amazing hotel options in an appealing way. Each hotel they feature has been thoroughly reviewed in order to become a hotel on their site. The Tablet team prides itself in having a background in travel, architecture, and design. This allows them to focus on quality, unique hotels with attention to detail. They also mention that they have zero tolerance for boredom. Overall, it fulfills the desire to want to stay at more than a standard chain hotel and provides hotel experiences worthwhile.
You can make reservations directly on the Tablet Hotel site, and the price is the lowest you can find. Some specific hotels I've discovered (and have had the pleasure to stay at) through Tablet Hotels are: Hotel Giraffe in New York City, Sundance Resort in Provo, Utah, International House in New Orleans, and Lungarno Suites in Florence, Italy.
www.tablethotels.com